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Dermatology

Itch Signaling and Neuroimmune Crosstalk

Dr. Kim delves into the role of itch signaling pathways and their relationship with the neuroimmune axis in type 2 inflammation. This connection is key to understanding how itch becomes a hallmark symptom in AD, PN, and CSU.
Brian Kim
MD
Brian Kim

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Learning objectives

  • Describe the role of type 2 inflammation in neuroimmune dysregulation, neuronal sensitization, and itch pathway activation​ 
  • Discuss how the cellular and molecular basis of specific neuroimmune interactions may help determine the disease-specific nature of itch and qualitative differences in itch in different disease states 
Tags
mechanism of diseasetype 2 inflammationitchneuroimmune mechanismscytokineschronic inflammation
MAT-US-2500391 v1.0 -P Exp Date: 08/01/2026

About this expert

Dermatology

Brian Kim

MD

Professor, Vice Chair of Research, and Site Chair of Mount Sinai West, Icahn School of Medicine, NY, US

See author’s profile
Brian Kim

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Sanofi and Regeneron are global leaders in pharmaceutical development, each with a long history of supporting frontline physicians to improve human health and reduce the burden of disease. Driven by the same commitment to patients and their families, Sanofi and Regeneron have partnered to take on type 2 inflammation and the range of chronic conditions in which excessive inflammation plays a role.

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