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Dermatology

A Tale of Two Itches: Bridging the Gap With Type 2 Inflammation in Prurigo Nodularis and Chronic Spontaneous Urticaria

Dr. Elmariah, Professor Metz, and Dr. Kim discuss the unique clinical presentations of PN and CSU and explore the shared and distinct pathophysiological underpinnings of itch and inflammation in both diseases, with a focus on the roles of type 2 cytokines at the neuroimmune axis In PN and CSU

Sarina Elmariah
Martin Metz
Brian Kim
MD, PhD
Sarina Elmariah +2 more

Learning objectives

  • Comprehend the unique and significant burdens associated with chronic itch and skin lesions in PN and CSU
  • Understand the diverse actions of type 2 cytokines at the neuroimmune axis and how they perpetuate chronic itch and inflammation in PN and CSU
Tags
symposium
MAT-US-2403617 v1.0 - P Exp Date: 04/03/2026

About these experts

Dermatology
MD, PhD

Sarina Elmariah

Associate Professor and Dermatology Director at the UCSF Centre for Itch and Neurosensory Disorders at the University of California in San Francisco, California, US

Allergy/Immunology
MD

Martin Metz

Professor in the Department of Dermatology and Allergy, Head of Translational Research, and Deputy Head of Clinical Trials | Charité – Universitätsmedizin, Berlin, Germany

Dermatology
MD

Brian Kim

Professor, Vice Chair of Research, and Site Chair of Mount Sinai West, Icahn School of Medicine, NY, US

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Sanofi and Regeneron are global leaders in pharmaceutical development, each with a long history of supporting frontline physicians to improve human health and reduce the burden of disease. Driven by the same commitment to patients and their families, Sanofi and Regeneron have partnered to take on type 2 inflammation and the range of chronic conditions in which excessive inflammation plays a role.

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