This video presentation of the full March 2024 ADVENT Atopic Dermatitis (AD) symposium, hosted in San Diego, California, features Dr. Eric Simpson, Dr. Katrina Abuabara, and Dr. Lawrence Eichenfield. The faculty present the latest information around the inflammatory processes in AD that promote a wide range of systemic and local effects, emphasizing the impact they have on patients’ quality of life. The faculty also discuss how these processes and burdens vary at specific life stages and may accumulate over time if left unchecked.