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Dermatology

Type 2 Inflammation is the Predominant Pathway in AD from Infancy to Adulthood

Breaking down type 2 inflammation as the predominant inflammatory pathway in AD through to adulthood from biomarker studies.

Amy Paller
MD, MS
Amy Paller

Learning objectives

  • Observe the large increase in IL-13, a key type 2 cytokine, in patients of all ages with AD
  • Identify age-related increases in some cytokines in both normal and AD patients

Description

In this short video, Dr. Amy Paller compares the cytokine subset development from infancy to adulthood in healthy patients with profiles in AD patients, noting the key differences that support the dominant role of type 2 inflammatory pathway in AD.

Tags
mechanism of disease
MAT-GLB-2200548 V2 03/2022

About this expert

Dermatology

Amy Paller

MD, MS

Walter J. Hamlin Professor and Chair of Dermatology; Professor of Pediatrics at Northwestern University, Evanston, Illinois, US

See author’s profile
Amy Paller

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Sanofi and Regeneron are global leaders in pharmaceutical development, each with a long history of supporting frontline physicians to improve human health and reduce the burden of disease. Driven by the same commitment to patients and their families, Sanofi and Regeneron have partnered to take on type 2 inflammation and the range of chronic conditions in which excessive inflammation plays a role.

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