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Dermatology

Mast Cells and the Neuroimmune Axis in CSU

A review of the neuroimmune mechanisms and activation of mast cells that result in itch in CSU.

Thomas Casale
MD
Thomas Casale

Learning objectives

  • Discuss the pathophysiological processes mediating pruritus in AD, PN, and CSU​
  • Describe how type 2 inflammatory cytokines are involved in inducing and amplifying pruritus in AD, PN, and CSU​
  • Explore the shared and distinct mechanisms of pruritus in AD, PN, and CSU​

Description

In this ADVENT symposium at the 2023 ADVENT FORUM, “Itch: The Common Thread in Dermatological Type 2 Inflammation (AD, PN, & CSU)​”, Stephan Weidinger, MD, PhD (University Hospital Schleswig-Holstein Campus Kiel, Kiel, Germany), Eric Simpson, MD, MCR (Oregon Health & Science University, Portland, OR, USA), Raj Chovatiya, MD, PhD (George Washington University School of Medicine and Health Sciences, Washington DC, USA) and Thomas B. Casale, MD (University of South Florida, USA) discussed the shared and unique neuroimmune mechanisms and supporting data demonstrating the generation of itch across AD, PN, and CSU.

MAT-GLB-2306039 V1 12/2023

About this expert

Allergy/Immunology

Thomas Casale

MD

Professor of Medicine and Pediatrics; Chief of Clinical and Translational Research, University of South Florida, Tampa, United States

See author’s profile
Thomas Casale

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