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Dermatology

A brief overview of the pathophysiology of PN

Dr. Chovatiya explains that PN is primarily a chronic itch disease with a complex pathophysiology involving neuronal changes, type 2 inflammation, and fibrotic skin processes, affecting patients' overall well-being.

Raj Chovatiya
MD, PhD, MSCI
Raj Chovatiya

Learning objectives

  • Recognize the involvement of nervous system changes, including nerve density, activity, and sensitization, as well as the role of type 2 inflammation in prurigo nodularis
  • Identify the multifaceted impact of prurigo nodularis on patients, clinical signs including-itch, lesions, sleep dysregulation, and mental health disturbances.
Tags
mechanism of diseaseexpert insightstype 2 inflammation
MAT-GLB-2403263- 1.0 - 07/2024

About this expert

Dermatology

Raj Chovatiya

MD, PhD, MSCI

Assistant Professor of Dermatology at the Northwestern University Feinberg School of Medicine in Chicago, US

See author’s profile
Raj Chovatiya

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