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Dermatology

A brief overview of the pathophysiology of PN

Dr. Chovatiya explains that PN is primarily a chronic itch disease with a complex pathophysiology involving neuronal changes, type 2 inflammation, and fibrotic skin processes, affecting patients' overall well-being.
Raj Chovatiya
MD, PhD, MSCI
Raj Chovatiya

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Learning objectives

  • Recognize the involvement of nervous system changes, including nerve density, activity, and sensitization, as well as the role of type 2 inflammation in prurigo nodularis
  • Identify the multifaceted impact of prurigo nodularis on patients, clinical signs including-itch, lesions, sleep dysregulation, and mental health disturbances.
Tags
mechanism of diseaseexpert insightstype 2 inflammation
MAT-GLB-2403263- 1.0 - 07/2024

About this expert

Dermatology

Raj Chovatiya

MD, PhD, MSCI

Assistant Professor of Dermatology at the Northwestern University Feinberg School of Medicine in Chicago, US

See author’s profile
Raj Chovatiya

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Sanofi and Regeneron are global leaders in pharmaceutical development, each with a long history of supporting frontline physicians to improve human health and reduce the burden of disease. Driven by the same commitment to patients and their families, Sanofi and Regeneron have partnered to take on type 2 inflammation and the range of chronic conditions in which excessive inflammation plays a role.

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