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Dermatology

The Role of Mast Cells, Basophils, and Type 2 Cells and Cytokines in CSU

The pathophysiology of chronic spontaneous urticaria (CSU) is complex and involves mast cell degranulation and elements of type 2 inflammation. Learn more about the role of mast cells, basophils, and type 2 inflammatory cells and cytokines involved in the pathophysiology of CSU.

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Learning objectives

  • Review the role of mast cells as a driver of CSU pathophysiology
  • Describe the specific roles of type 2 cytokines in the pathophysiologic processes in CSU
  • Review the role of mast cells and basophils as drivers of CSU pathophysiology
Tags
disease backgroundmechanism of disease
MAT-US-2410605 v1.0 - P Exp Date: 10/22/2025

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Sanofi and Regeneron are global leaders in pharmaceutical development, each with a long history of supporting frontline physicians to improve human health and reduce the burden of disease. Driven by the same commitment to patients and their families, Sanofi and Regeneron have partnered to take on type 2 inflammation and the range of chronic conditions in which excessive inflammation plays a role.

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