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Dermatology

The Role of Mast Cells, Basophils, and Type 2 Cells and Cytokines in CSU

The pathophysiology of chronic spontaneous urticaria (CSU) is complex and involves mast cell degranulation and elements of type 2 inflammation. Learn more about the role of mast cells, basophils, and type 2 inflammatory cells and cytokines involved in the pathophysiology of CSU.

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Learning objectives

  • Review the role of mast cells as a driver of CSU pathophysiology
  • Describe the specific roles of type 2 cytokines in the pathophysiologic processes in CSU
  • Review the role of mast cells and basophils as drivers of CSU pathophysiology
MAT-US-2410605 v1.0 - P Exp Date: 10/22/2025

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