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Dermatology

AD, PN, and CSU: Similar Inflammation, Distinct Itch

In this final video, Dr. Kim compares the shared and distinct pathophysiological features that drive itch in AD, PN, and CSU. He ties together the knowledge from earlier episodes, highlighting the similarities and differences in the mechanisms of itch across these diseases.
Brian Kim
MD
Brian Kim

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Learning objectives

  • Explain how AD, PN, and CSU are distinct diseases, with each exhibiting unique characteristics—from variable itch quality to underlying pathophysiology and skin manifestations​
  • Describe how the spatiotemporal sequence of type 2 immune cells and mediators generates itch and triggers neuroinflammation in AD, PN, and CSU
Tags
mechanism of diseasetype 2 inflammationitchneuroimmune mechanismscytokineschronic inflammation
MAT-US-2500391 v1.0 -P Exp Date: 08/01/2026

About this expert

Dermatology

Brian Kim

MD

Professor, Vice Chair of Research, and Site Chair of Mount Sinai West, Icahn School of Medicine, NY, US

See author’s profile
Brian Kim

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Sanofi and Regeneron are global leaders in pharmaceutical development, each with a long history of supporting frontline physicians to improve human health and reduce the burden of disease. Driven by the same commitment to patients and their families, Sanofi and Regeneron have partnered to take on type 2 inflammation and the range of chronic conditions in which excessive inflammation plays a role.

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