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Dermatology

The Science Behind the Scratch: Pathophysiology of Age-Related Itch

Dr. Butler delves into the multifaceted biological mechanisms, including type 2 inflammation, that drive chronic pruritus in older adults. He explains how age-related changes contribute to epidermal barrier dysfunction, neuropathic damage, and immune decline, leading to chronic pruritus.
Daniel Butler
MD
Daniel Butler

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Learning objectives

  • Provide a detailed scientific understanding of the unique pathophysiological changes in aging skin that contribute to pruritus, focusing specifically on immunosenescence, neural hypersensitivity, and barrier dysfunction, to better comprehend the complexit
Tags
type 2 inflammationmechanism of diseasechronic pruritus
MAT-US-2603377 v1.0 - P Expiration Date: 02/18/2028

About this expert

Dermatology

Daniel Butler

MD

Assistant Dean of Student Affairs, University of Arizona College of Medicine, Tuscon, AZ

See author’s profile
Daniel Butler

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Sanofi and Regeneron are global leaders in pharmaceutical development, each with a long history of supporting frontline physicians to improve human health and reduce the burden of disease. Driven by the same commitment to patients and their families, Sanofi and Regeneron have partnered to take on type 2 inflammation and the range of chronic conditions in which excessive inflammation plays a role.

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