Pulmonology

A view into the Airway: The Pathophysiology and Clinical Relevance of Mucus Plugs in Asthma

Explore the role of type 2 inflammation in the production of mucus plugs in asthma and the effects these plugs can have on patients.

Learning objectives

  • Describe the role of type 2 inflammation in driving mucus plug formation in the airways of asthma patients
  • Identify how mucus plug scores can be assessed via CT imaging
  • Understand the association of high mucus scores with asthma outcomes including reduced lung function and more frequent exacerbations

Description

Mucus is an important part of the normal processes in healthy lungs; however, when mucus is produced in excess due to a type 2 inflammatory response, it can negatively impact asthma patients. In this video, explore the process of mucus plug formation driven by type 2 inflammation, learn how mucus plugs are quantified, and find out the impact of mucus plugging on clinical outcomes for asthma patients. 

MAT-US-2506613 v1.0 - P Exp. date 05/19/2027

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