Dermatology

Prurigo Nodularis: Type 2 Inflammation Links Neuronal Dysfunction and Fibrosis

This infographic highlights how PN is driven by type 2 inflammation, linking immune dysregulation, fibroblast activation, and neuronal dysfunction to nodule formation. It also shows how cytokine-mediated changes in neuronal architecture increase excitability and chronic itch, where resulting lesions and scarring significantly impact patients’ psychological well-being.

Related resources

Learning objectives

  • Understand how type 2 inflammation in prurigo nodularis drives immune dysregulation, neuronal dysfunction, and dermal fibrosis, leading to nodule formation
MAT-US-2603375 v1.0 -P Expiration Date: 02/25/2028