Join Dr. Amber Luong and Dr. Marjolein Cornet as they break down the critical issue of oral corticosteroid (OCS) use in chronic rhinosinusitis with nasal polyps (CRSwNP). This conversation explores the often-underrecognized short-term, long-term, and cumulative risks associated with OCS, emphasizing the compounded challenges for patients with comorbid type 2 inflammatory diseases like asthma. They also discuss the current landscape of OCS use and advocate for OCS-sparing strategies and better multidisciplinary coordination to improve outcomes and minimize steroid exposure for patients with CRSwNP.