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60 search results for: mechanism of disease

expert video

Contributions of Type 2 Cytokines to Chronic Pruritus in AD, PN, and CSU

2 min

Dermatology

Dr. Elmariah introduces the multiple roles of type 2 cytokines in chronic itch.

expert video

How Does Protective Type 2 Immunity Become Harmful Type 2 Inflammation?

9 min

Dermatology

In this video from the March 2025 ADVENT symposium in Orlando, Florida, Dr. Eric Simpson discusses how protective type 2 immunity can become dysregulated, leading to harmful type 2 inflammation. The associated inflammatory process can contribute to the pathophysiology of several dermatological diseases, including AD, PN, CSU, and BP.

Role <b>of</b> Type 2 Inflammation in Prurigo Nodularis Part 2: Itch and Skin Lesions

expert video

Role of Type 2 Inflammation in Prurigo Nodularis Part 2: Itch and Skin Lesions

13 min

Dermatology

Dive deeper into the specific role of type 2 inflammation in neuroimmune dysregulation and dermal fibrosis that leads to itch and skin lesions seen in patients with prurigo nodularis with Dr. Raj Chovatiya in the second part of this discussion.

Role <b>of</b> Type 2 Inflammation in Prurigo Nodularis Part 1: Overview <b>of</b> Type 2 Inflammation

expert video

Role of Type 2 Inflammation in Prurigo Nodularis Part 1: Overview of Type 2 Inflammation

8 min

Dermatology

Join Dr. Raj Chovatiya as he provides an overview of the impact of type 2 inflammation in prurigo nodularis in the first part of this discussion.

expert video

Under the Skin: Considerations for Atopic Dermatitis and Prurigo Nodularis in Clinical Practice

42 min

Dermatology

In this ADVENT symposium at the 2024 Diversity in Dermatology conference, experts Dr(s) Sarina Elmariah and Mona Shahriari engage in a dynamic discussion on diagnostic considerations for atopic dermatitis and prurigo nodularis and how clinical signs and itch in these diseases are impacted by type 2 inflammation.

expert video

Pathophysiology of Blister Formation in Bullous Pemphigoid

2 min

Dermatology

Professor Enno Schmidt discusses the pathophysiology of BP, focusing on the role of type 2 inflammation and blister formation

The Role <b>of</b> Mast Cells, Basophils, and Type 2 Cells and Cytokines in CSU

Infographic

The Role of Mast Cells, Basophils, and Type 2 Cells and Cytokines in CSU

5 min

Dermatology

The pathophysiology of chronic spontaneous urticaria (CSU) is complex and involves mast cell degranulation and elements of type 2 inflammation. Learn more about the role of mast cells, basophils, and type 2 inflammatory cells and cytokines involved in the pathophysiology of CSU.

interactivity

Skin Dyspigmentation In Prurigo Nodularis (PN)

10 min

Dermatology

This infographic illustrates the clinical manifestations, pathophysiology and impact on patients of skin dyspigmentation in Prurigo Nodularis.

interactivity

Skin Dyspigmentation In Prurigo Nodularis (PN)

10 min

Dermatology

This infographic illustrates the clinical manifestations, pathophysiology and impact on patients of skin dyspigmentation in Prurigo Nodularis.

IRS-ISIAN 2024 | The Importance <b>of</b> Understanding Smell Loss and Congestion in CRSwNP

expert video

IRS-ISIAN 2024 | The Importance of Understanding Smell Loss and Congestion in CRSwNP

15 min

Rhinology

Prof. Joaquim Mullol presents on the proposed mechanisms of smell loss and nasal congestion in CRSwNP.

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Sanofi and Regeneron are global leaders in pharmaceutical development, each with a long history of supporting frontline physicians to improve human health and reduce the burden of disease. Driven by the same commitment to patients and their families, Sanofi and Regeneron have partnered to take on type 2 inflammation and the range of chronic conditions in which excessive inflammation plays a role.

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