223 search results for: burden of disease

What Went Wrong? How Dysregulated Type 2 Immunity Contributes to AD, PN, CSU, and BP
On Demand
What Went Wrong? How Dysregulated Type 2 Immunity Contributes to AD, PN, CSU, and BP

The March 2025 ADVENT symposium in Orlando, Florida brought together 4 dermatology experts to explore the evolving science of type 2 inflammation. Type 2 inflammation plays a central role in the pathophysiology of multiple dermatological diseases, driving chronic immune dysregulation that affects patients with atopic dermatitis (AD) prurigo nodularis (PN), chronic spontaneous urticaria (CSU) and bullous pemphigoid (BP). Understanding the mechanisms behind type 2 inflammation is key to advancing care and improving patient quality of life.

How Does Protective Type 2 Immunity Become Harmful Type 2 Inflammation?
Dermatology
How Does Protective Type 2 Immunity Become Harmful Type 2 Inflammation?
expert video

In this video from the March 2025 ADVENT symposium in Orlando, Florida, Dr. Eric Simpson discusses how protective type 2 immunity can become dysregulated, leading to harmful type 2 inflammation. The associated inflammatory process can contribute to the pathophysiology of several dermatological diseases, including AD, PN, CSU, and BP.

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Master Clinician Video | Advanced Clinical Practice in EoE (Full)
Gastroenterology
Master Clinician Video | Advanced Clinical Practice in EoE (Full)
videoanimation

Learn how a food bolus impaction event can help identify a patient with EoE and the importance of multiple disease domains in assessing EoE.

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AD, PN, and CSU: Similar Inflammation, Distinct Itch
Dermatology
AD, PN, and CSU: Similar Inflammation, Distinct Itch
expert video

In this final video, Dr. Kim compares the shared and distinct pathophysiological features that drive itch in AD, PN, and CSU. He ties together the knowledge from earlier episodes, highlighting the similarities and differences in the mechanisms of itch across these diseases.

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ADVENT Forum 2025 On Demand page
On Demand
ADVENT Forum 2025 On Demand page

Watch on-demand expert soundbites recorded at the April 2025 ADVENT Forum in Lisbon, Portugal, featuring dermatology and immunology perspectives on mechanisms and clinical practice. Topics range from disease mechanism to patient care and quality of life, spanning atopic dermatitis (AD), prurigo nodularis (PN), chronic spontaneous urticaria (CSU) and bullous pemphigoid (BP).

Charting the Future: Preventing the Atopic March
Dermatology
Charting the Future: Preventing the Atopic March
expert video

In this clip from the April WCPD 2025 symposium, Dr Eulàlia Baselga highlights the multidimensional burden of uncontrolled AD and how the various burdens contribute to Cumulative Life Course Impairment (CLCI).

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UEGW 2024 | Something to Chew On: Exploring the Management <b>of</b> EoE
Gastroenterology
UEGW 2024 | Something to Chew On: Exploring the Management of EoE
expert video

Prof. Salvatore Oliva and Dr. Milli Gupta discuss the importance of long-term care and multidimensional assessment.

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Epidemiology and Pathophysiology <b>of</b> AD in Children
Dermatology
Epidemiology and Pathophysiology of AD in Children
expert video

In this expert interview video focusing on topics from the October 2024 ADVENT symposium at EAPS in Vienna, Austria, Dr Christine Bangert discusses the epidemiology of AD in children and the role of type 2 cytokines in driving the pathophysiology of the disease

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Atopic and Nonatopic Comorbidities in AD and the Importance <b>of</b> Early Intervention
Dermatology
Atopic and Nonatopic Comorbidities in AD and the Importance of Early Intervention
expert video

In this soundbite video from the April 2025 ADVENT Forum in Lisbon, Portugal, Dr Amy Paller reviews the increased risk of atopic and nonatopic comorbidities associated with atopic dermatitis and discusses the potential of early intervention to mitigate their development.

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Scratching the Surface: Understanding Itch in Prurigo Nodularis
Dermatology
Scratching the Surface: Understanding Itch in Prurigo Nodularis
expert video

Join experts Drs. Raja Sivamani and Sarina Elmariah as they discuss the clinical signs and high patient burden of PN, explore PN pathophysiology, and examine diagnostic challenges.

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Hives vs. Itch: The Role <b>of</b> Type 2 Inflammation in Itch in CSU
Dermatology
Hives vs. Itch: The Role of Type 2 Inflammation in Itch in CSU
expert video

Join Dr. Kim as he explores the pathogenesis of CSU and the mechanisms that promote itch in CSU. The complex interplay of type 2 inflammation in CSU is examined, offering insights into its unique challenges for patients and clinicians alike.

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On Demand
Bridging the Gap in EoE: Innovative Strategies for Seamless Transition of Care

Join leading experts in EoE, Thomas Greuter, MD, Edoardo Vincenzo Savarino, MD, PhD, and Carla Giordano, MD, PhD, as they use a case-based approach to explore the impact of chronic type 2 inflammation in EoE and outline strategies for optimizing transition of care and monitoring disease progression. They review the latest clinical evidence on therapeutic management and share insights from their own practice to support shared decision-making in the long-term care of EoE.