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Rhinology
On demand events
IFOS 2023 | Type 2 Inflammation and Clinically Relevant Improvements in CRSwNP
Dr. Stella Lee and Profs. Peter Hellings and Wytske Fokkens discuss type 2 inflammation, partnering with patients to improve outcomes, and real-world data on biologic effectiveness in CRSwNP.
MD
Stella Lee +2 more
On demand materials
Learning objectives
- Review the inflammatory endotypes observed in CRSwNP, zooming in on the key role of type 2 cytokines, IL-4, IL-13, and IL-5
- Understand the underappreciated burden on health-related quality of life, and the importance of bringing patients into the decision-making process
- Define the concepts of statistical significance and clinical importance and the advantages of considering clinically important symptom improvements in patients with CRSwNP
- Review evidence of improvements in olfaction with surgery and biologics from real-world effectiveness studies and randomized controlled trials and safety of biologics in patients with CRSwNP
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