Professor Sarina Elmariah highlights the multifaceted role of IL-4 and IL-13 in driving dermal fibrosis in prurigo nodularis, which leads to persistent scarring and dyspigmentation that significantly contribute to patients' embarrassment, anxiety, depression, and self-esteem.
This symposium explores the key role type 2 inflammation plays in atopic dermatitis and prurigo nodularis and debunks common misconceptions about these skin diseases with key insights from Drs Ahuva Cices and Naiem Issa.
Dr. Naiem Issa examines the shared and distinct features of atopic dermatitis and prurigo nodularis, highlighting the role of type 2 inflammation in both diseases.
Dr. Naiem Issa debunks common misconceptions in prurigo nodularis with key clinical insights.

Dr. Jason Hawkes provides key pathophysiologic insights and debunks common misconceptions surrounding atopic dermatitis.
Dr. Ahuva Cices provides key pathophysiologic insights and dispels common misconceptions surrounding atopic dermatitis.
Dr. Lakshi Aldredge sets the record straight regarding common misconceptions about prurigo nodularis.
In this episode, Dr. Sarina Elmariah and Dr. Brian Kim explore prurigo nodularis (PN), with a focus on severe itch, fibrotic skin lesions, and their impact on patients’ quality of life. They discuss PN epidemiology, common comorbidities, and the challenges of managing multimorbid patients, while breaking down the neuroimmune mechanisms, highlighting the role of type 2 cytokines in itch and lesion development.
Dr. Daniel Butler tackles prevalent misconceptions surrounding prurigo nodularis.
Dr. David Cotter debunks prevalent misconceptions surrounding atopic dermatitis by providing essential insights into its pathophysiology.
Follow Janet, a hypothetical patient, as she navigates the difficult journey of bullous pemphigoid, starting with symptom onset to diagnosis.