54 search results for: coexisting diseases

Distinct Mechanisms Drive Inflammation and Itch in Chronic, Type 2 Inflammatory <b>Diseases</b>
Type 2 Inflammation
Distinct Mechanisms Drive Inflammation and Itch in Chronic, Type 2 Inflammatory Diseases
expert video

In this soundbite video from the April 2025 ADVENT Forum in Lisbon, Portugal, Dr Brian Kim provides an overview of itch in type 2 inflammatory skin diseases and explains how the shared and unique mechanisms that drive inflammation and itch mediate each disease in distinct ways.

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The Role of Type 2 Inflammation in Multiple Disease Trajectories
Dermatology
The Role of Type 2 Inflammation in Multiple Disease Trajectories
Infographic

How type 2 inflammation drives atopic dermatitis and underlies other atopic diseases across multiple disease trajectories including the atopic march.

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The Compounded Burden of CRSwNP and Asthma
Pulmonology
The Compounded Burden of CRSwNP and Asthma
interactivity

This infographic illustrates the compounded burden of coexisting CRSwNP and asthma and explains how type 2 inflammation underlies both conditions and impacts clinical outcomes in patients.

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ESPGHAN 2025 Pediatric EoE: Early Identification & Type 2 Comorbidity
Gastroenterology
ESPGHAN 2025 Pediatric EoE: Early Identification & Type 2 Comorbidity
expert video

Dr Tzivinikos discusses the importance of early identification and management of pediatric EoE to improve long-term outcomes.

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Spotlight on Type 2 Inflammation in the Upper and Lower Airways
Pulmonology
Spotlight on Type 2 Inflammation in the Upper and Lower Airways
expert video

In this video soundbite from the EAACI 2025 symposium, Dr. Zuzana Diamant explains pathophysiological mechanisms underlying asthma and CRSwNP, and how type 2 inflammatory cytokines drive airway remodelling in patients with severe asthma. Additionally, patients with co-existing asthma and CRSwNP have a higher type 2 inflammatory burden than patients with asthma alone.

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From Protective Type 2 Immunity to Aberrant Type 2 Inflammation
Type 2 Inflammation
From Protective Type 2 Immunity to Aberrant Type 2 Inflammation
expert video

In this soundbite video from the April 2025 ADVENT Forum in Lisbon, Portugal, Prof. Oscar Palomares explains how type 2 immunity evolved to protect against parasites, venoms, and toxins, and how its dysregulation can result in aberrant type 2 inflammation underlying multiple chronic inflammatory diseases.

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Type 2 Inflammation
Dermatology
Type 2 Inflammation
expert video

In this video from the 2024 Society for Pediatric Dermatology Symposium held in Toronto, Canada, Dr. Peter Lio, MD and Dr. Amy Paller, MD discusses the multifaceted nature of atopic diseases, including environmental triggers, key Type 2 inflammatory mechanisms, and associated health risks, to understand the importance of early intervention in managing and potentially modifying disease progression.

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From Symptoms to Signaling: Type 2 Inflammation Underlying AD/PN
Dermatology
From Symptoms to Signaling: Type 2 Inflammation Underlying AD/PN
expert video

Dr. Naiem Issa examines the shared and distinct features of atopic dermatitis and prurigo nodularis, highlighting the role of type 2 inflammation in both diseases.

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The Type 2 Inflammatory Link in AD, CSU, and PN
Dermatology
The Type 2 Inflammatory Link in AD, CSU, and PN
expert video

Dr. Jason Hawkes explores the unique clinical manifestations of atopic dermatitis, chronic spontaneous urticaria, and prurigo nodularis, while highlighting the shared role of type 2 inflammation across these distinct diseases.

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How Does Protective Type 2 Immunity Become Harmful Type 2 Inflammation?
Dermatology
How Does Protective Type 2 Immunity Become Harmful Type 2 Inflammation?
expert video

In this video from the March 2025 ADVENT symposium in Orlando, Florida, Dr. Eric Simpson discusses how protective type 2 immunity can become dysregulated, leading to harmful type 2 inflammation. The associated inflammatory process can contribute to the pathophysiology of several dermatological diseases, including AD, PN, CSU, and BP.

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What Went Wrong? How Dysregulated Type 2 Immunity Contributes to AD, PN, CSU, and BP
On Demand
What Went Wrong? How Dysregulated Type 2 Immunity Contributes to AD, PN, CSU, and BP

The March 2025 ADVENT symposium in Orlando, Florida brought together 4 dermatology experts to explore the evolving science of type 2 inflammation. Type 2 inflammation plays a central role in the pathophysiology of multiple dermatological diseases, driving chronic immune dysregulation that affects patients with atopic dermatitis (AD) prurigo nodularis (PN), chronic spontaneous urticaria (CSU) and bullous pemphigoid (BP). Understanding the mechanisms behind type 2 inflammation is key to advancing care and improving patient quality of life.

Navigating Atopic Dermatitis and Hand and Foot Dermatitis: Clinical Manifestations and Pathophysiology
Dermatology
Navigating Atopic Dermatitis and Hand and Foot Dermatitis: Clinical Manifestations and Pathophysiology
expert video

Watch Drs. Simpson and Armstrong explore the clinical presentations, diagnostic challenges, and significant burdens experienced by patients with atopic dermatitis and hand and foot dermatitis, as well as the role type 2 inflammation plays in both of these diseases.

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