This symposium delves into the pivotal role of type 2 inflammation in diverse skin conditions, including atopic dermatitis, prurigo nodularis, chronic spontaneous urticaria, and bullous pemphigoid. It highlights both shared and distinct disease mechanisms and patient burdens, providing crucial insights for optimizing clinical management strategies through a series of engaging panel discussions with Drs Eichenfield, Elmariah, Culton, and Hawkes.
Dr Donna Culton walks through the pathophysiology of type 2 inflammation in inflammatory skin diseases, using bullous pemphigoid as an example. Drs Eichenfield, Elmariah, and Hawkes join to discuss the role of type 2 inflammation across atopic dermatitis, prurigo nodularis, and chronic spontaneous urticaria, respectively.

Dr. Donna Culton describes the heterogeneous presentation and diagnosis of bullous pemphigoid at EADV 2025

Dr. Donna Culton discusses the elevated mortality risk in patients with bullous pemphigoid at EADV 2025
Join Drs. Victoria Werth and Teri Greiling as they explain the autoimmunity driving bullous pemphigoid (BP), as well as the important role type 2 inflammation plays in BP.
Join Dr. Teri Greiling as she discusses the heterogeneous clinical presentations seen in bullous pemphigoid (BP). She also shares diagnostic challenges, including the unclear epidemiology and the extensive differential diagnoses faced by patients with BP.
Join Dr. Victoria Werth as she shares the unmet needs and management challenges experienced by patients with bullous pemphigoid (BP), including physical, mental, socioeconomic, and treatment-related burdens. She expands on the comorbidities and increased mortality rates these patients may face.
Dr Sarina Elmariah highlights the clinical challenges in diagnosing inflammatory skin diseases, using prurigo nodularis as a case study. Drs Culton, Eichenfield, and Hawkes then join in to discuss additional challenges and complexities when diagnosing other skin diseases.
Watch Dr. Donna Culton and Prof. Ulrike Raap at EADV 2025 as they explore the clinical presentation and diagnosis of BP and break down the underlying pathophysiology including the roles of autoimmunity and key inflammatory pathways such as Type 2 inflammation.
Experience this engaging presentation by Dr. Donna Culton, Prof. Dédée Murrell, and Prof. Ulrike Raap, who highlight the heterogeneous clinical presentations of BP and its burden, delve beneath the surface into how autoimmunity and predominantly type 2 inflammation mediate the disease, and explore the evolving toolbox of current approaches in BP management.

Welcome to the BP learning hub focused on key scientific education on bullous pemphigoid, featuring ADVENT resources.
Professor Joost Meijer discusses the complex etiology and diagnosis of BP