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Type 2 Inflammation
On demand events

World Congress on Itch 2023 Symposium: Itch in AD, PN, and CSU: Underlying Mechanisms and the Role of Type 2 Inflammation

Exploration of the shared mechanisms of itch across AD, PN, and CSU as well as the distinct ways itch manifests in each disease.

Brian Kim
Sarina Elmariah
MD
Brian Kim +1 more

On demand materials

Learning objectives

  • Describe the role of type 2 inflammation in the development of itch in AD, PN, and CSU
  • Discuss the contribution of neuroimmune axis dysregulation to the development of itch in AD, PN, and CSU
  • Explore disease-specific combinations of type 2 inflammatory mediators that may underlie disease-specific itch in AD, PN, and CSU

Description

The chronic skin conditions atopic dermatitis (AD), prurigo nodularis (PN), and chronic spontaneous urticaria (CSU) have distinct clinical signs but share the common, debilitating symptom of itch. In AD, PN, and CSU, type 2 inflammation and a dysregulated neuroimmune axis underlie itch pathophysiology. This symposium explores the shared mechanisms of itch across these diseases, as well as the distinct ways itch manifests in each condition. Understanding the pathomechanisms of itch will help to address the substantial burden of these chronic pruritic conditions.

MAT-US-2309780 v1.0 - P Expiration Date: 02/12/2026

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