How type 2 inflammation drives atopic dermatitis and underlies other atopic diseases across multiple disease trajectories including the atopic march.
This educational tool aims to review the current understanding of atopic dermatitis and the development of atopic comorbidities. It outlines the well-known concept of the atopic march, the development of other atopic diseases such as asthma and rhinitis independent of AD, the role of type 2 inflammation underpinning these diseases, and the potential implications of targeting systemic type 2 inflammation to alter disease course.