This cross-TA joint plenary session focused on the challenges faced by patients with diseases driven by type 2 inflammation. A panel of esteemed faculty representing adult and pediatric type 2 disease area specialties discussed strategies to improve quality of life, address burden of disease, and ways to prioritize patient-centered care. Panelists were Profs Klaus Rabe, Sharon Dell, Anju Peters, Milli Gupta, Eric Simpson, Stella Lee, and Oscar Palomares(moderator).