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32 search results for: itch

Type 2 Inflammation and Neuronal Sensitization in AD and PN
interactivity

Type 2 Inflammation and Neuronal Sensitization in AD and PN

Dermatology
Mechanisms of itch in normal skin and the effect of type 2 inflammation on neurons leading to chronic itch in atopic dermatitis and prurigo nodularis.
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Contributions of Type 2 Cytokines to Chronic Pruritus in AD, PN, and CSU
expert video

Contributions of Type 2 Cytokines to Chronic Pruritus in AD, PN, and CSU

Dermatology
Dr. Elmariah introduces the multiple roles of type 2 cytokines in chronic itch.
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AD, PN, and CSU: Distinct, Pruritic Diseases
expert video

AD, PN, and CSU: Distinct, Pruritic Diseases

Dermatology
Dr. Elmariah explains how AD, PN, and CSU are distinct diseases with the common, burdensome symptom of itch.
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Immune System, Microbiome and Neuroimmune Crosstalk in the Skin: Implications for AD
expert video

Immune System, Microbiome and Neuroimmune Crosstalk in the Skin: Implications for AD

Dermatology
The role of dysbiosis in the propagation of type 2 inflammation and itch in atopic dermatitis – a presentation from the ADVENT symposium at ISID 2023.
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The Burden of Atopic Dermatitis in Children – Daily Pruritis and Sleep Disturbance 
expert video

The Burden of Atopic Dermatitis in Children – Daily Pruritis and Sleep Disturbance 

Dermatology
Dr. Mark Koh provides insights on itch and its impact on sleep in children with AD.
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ADVENT On Air | Exploring PN as a Distinct and Unique Disease
Podcast

ADVENT On Air | Exploring PN as a Distinct and Unique Disease

Dermatology
Dr. Sonja Ständer and Dr. Shawn Kwatra discuss the unique features of prurigo nodularis (PN) as well as the characteristics that are shared with atopic dermatitis, and aim to raise awareness of PN among both physicians and patients.
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ADVENT On Air - Dermatology
Podcast

ADVENT On Air | Expert Discussions in Dermatology

Dermatology
Listen to the latest updates in type 2 inflammatory science and associated skin diseases, brought to you by leading dermatology experts in the field. ADVENT On Air podcasts feature scientific conversations that explore new research into the pathophysiology, clinical features, and disease burden for a range of dermatological diseases linked to type 2 inflammation, including atopic dermatitis (AD) and prurigo nodularis (PN). Hear new insights revealed through expert-led conversations below or in your preferred podcast app.

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Can advanced systemic therapies modify pathomechanisms in AD?
expert video

Can advanced systemic therapies modify pathomechanisms in AD?

Dermatology
Dr. Ramien discusses evidence showing that advanced therapies can modify the mechanisms of atopic dermatitis, improving skin barrier function, normalizing the skin microbiome, and reducing chronic itch.
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What Drives PN Disease? Exploring the Complexity of PN Pathophysiology
expert video

What Drives PN Disease? Exploring the Complexity of PN Pathophysiology

Dermatology
Dr. Brian Kim discusses the numerous contributors to PN pathophysiology, including type 2 inflammation, neuronal dysfunction, and dermal fibrosis, emphasizing the unique and overlapping roles of IL 31, IL-4 and IL-13 in its pathology.
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The Impact of Skin Fibrosis in Patients with Prurigo Nodularis
videoanimation

The Impact of Skin Fibrosis in Patients with Prurigo Nodularis

Dermatology
An animated infographic exploring the patient burden and pathophysiology of skin fibrosis in prurigo nodularis, specifically detailing how fibrotic pathways are driven and the key molecules involved.
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Targeting Type 2 Inflammation in Children with AD​
expert video

Targeting Type 2 Inflammation in Children with AD​

Dermatology
The impact of type 2 inflammation in itch and barrier dysfunction in atopic dermatitis – Presentation from the ADVENT symposium at EAACI 2023.
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Skin Barrier, Neuroimmune Axis, and Type 2 Inflammation in Atopic Dermatitis - Q&As
expert video

Skin Barrier, Neuroimmune Axis, and Type 2 Inflammation in Atopic Dermatitis - Q&As

Dermatology
Expert insights on the plasticity of inflammation, atopic dermatitis endotypes, and dysbiosis – Audience Q&A from the ADVENT symposium at ISID 2023.
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Sanofi and Regeneron are global leaders in pharmaceutical development, each with a long history of supporting frontline physicians to improve human health and reduce the burden of disease. Driven by the same commitment to patients and their families, Sanofi and Regeneron have partnered to take on type 2 inflammation and the range of chronic conditions in which excessive inflammation plays a role.

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