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Dermatology

Beyond Itch: The Multifaceted Role of IL-4/IL-13 in the Pathogenesis of PN

Professor Sarina Elmariah describes how IL-4 and IL-13, key drivers of type 2 inflammation, uniquely contribute to manifestations of prurigo nodularis beyond itch.
Sarina Elmariah
MD, PhD, MPH
Sarina Elmariah

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Learning objectives

  • Dissect the unique mechanisms by which type 2 inflammation drives the full spectrum of prurigo nodularis manifestations beyond itch
Tags
type 2 inflammationneuroimmune mechanismsIL-4IL-13chronic inflammation
MAT-GLB-2600443 - 1.0 - 02/2026

About this expert

Dermatology

Sarina Elmariah

MD, PhD, MPH

Associate Professor and Dermatology Director at the UCSF Centre for Itch and Neurosensory Disorders at the University of California in San Francisco, California, US

See author’s profile
Sarina Elmariah

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MAT-GLB-2302957 - 4.0 - 10/2025

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Sanofi and Regeneron are global leaders in pharmaceutical development, each with a long history of supporting frontline physicians to improve human health and reduce the burden of disease. Driven by the same commitment to patients and their families, Sanofi and Regeneron have partnered to take on type 2 inflammation and the range of chronic conditions in which excessive inflammation plays a role.

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Beyond Itch: The Multifaceted Role of IL-4/IL-13 in the Pathogenesis of PN