WCD 2023 Symposium: IL-4 and IL-13: Shared and Unique Roles in Atopic Dermatitis (AD) and Prurigo Nodularis (PN)

• Recognize that atopic dermatitis and prurigo nodularis are distinct diseases with commonalities and differences in clinical and pathophysiological characteristics
• Review barrier dysfunction in atopic dermatitis and share evidence supporting skin barrier normalization achieved by inhibiting type 2 cytokines
• Review the role of type 2 cytokines in dermal fibrosis and pruritus in prurigo nodularis

Atopic dermatitis and prurigo nodularis are dermatological conditions characterized by both common and distinct factors influencing their pathophysiology, presentation, and progression. In this ADVENT-sponsored symposium at the WCD 2023 Congress in Singapore, experts Mark Tang, MD (Mount Alvernia Hospital, Singapore), Lisa A. Beck, MD (University of Rochester, USA), and Gil Yosipovitch, MD (Miami Itch Center, USA), examined the shared and distinct clinical features between atopic dermatitis and prurigo nodularis.