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Pulmonology

ERS 2025 | Type 2 Severe Asthma “Unplugged”: Reducing Mucus to Improve Long-Term Patient Outcomes

Join leading pulmonologists Drs. Njira Lugogo, Simon Couillard, and Mario Castro, as they explore the role of type 2 inflammation in the pathogenesis of mucus plugging in the airways, the burden of excess mucus in patients with moderate-to-severe asthma, and how reducing airway mucus may lead to improved long-term patient outcomes.
Mario Castro
Simon Couillard
Njira Lugogo
MD, MPH
Mario Castro +2 more

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Learning objectives

  • Highlight the burden of mucus plugging in asthma​ and its correlation with lung function decline
  • Educate on the role of type 2 inflammation ​ in the development of mucus plugs
  • Explore the available clinical data supporting the impact on mucus plugging ​ and the disease-modifying potential of the current therapeutic landscape
Tags
asthma
MAT-GLB-2506730 - 1.0 - 12/2025

About these experts

Pulmonology
MD, MPH

Mario Castro

Chief, Pulmonary, Critical Care and Sleep Medicine; Vice Chair for Clinical and Translational Research, University of Kansas School of Medicine

Pulmonology
MD, MSc

Simon Couillard

Professor Couillard is a respirologist and the Québec Lung Association Chair of Respiratory Research at the Université de Sherbrooke, Canada. He leads a team investigating ways to use biomarkers to predict and prevent asthma attacks and improve asthma management.

Pulmonology
MD

Njira Lugogo

Dr. Lugogo is a Professor of Medicine in the Division of Pulmonary, Critical Care Medicine and is the Director of the Michigan Medicine Asthma Program. She is also the Program Director of INHALE, a statewide collaborative quality improvement program that focuses on improving the care of patients with asthma and COPD in Michigan.

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MAT-GLB-2302957 - 4.0 - 10/2025

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Sanofi and Regeneron are global leaders in pharmaceutical development, each with a long history of supporting frontline physicians to improve human health and reduce the burden of disease. Driven by the same commitment to patients and their families, Sanofi and Regeneron have partnered to take on type 2 inflammation and the range of chronic conditions in which excessive inflammation plays a role.

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