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Type 2 Inflammation

World Congress on Itch (WCI) 2023 | Miami

Exploration of the shared mechanisms of itch across AD, PN, and CSU as well as the distinct ways itch manifests in each disease.

Sarina Elmariah
Brian Kim
MD, PhD
Sarina Elmariah +1 more
Past event
7November2023
Location
JW Marriot
1109 Brickell Ave 33131 Miami, FL United States

Learning objectives

  • Describe the role of type 2 inflammation in the development of itch in AD, PN, and CSU
  • Discuss the contribution of neuroimmune axis dysregulation to the development of itch in AD, PN, and CSU
  • Explore disease-specific combinations of type 2 inflammatory mediators that may underlie disease-specific itch in AD, PN, and CSU

Description

The chronic skin conditions atopic dermatitis (AD), prurigo nodularis (PN), and chronic spontaneous urticaria (CSU) have distinct clinical signs but share the common, debilitating symptom of itch. In AD, PN, and CSU, type 2 inflammation and a dysregulated neuroimmune axis underlie itch pathophysiology. This symposium explores the shared mechanisms of itch across these diseases, as well as the distinct ways itch manifests in each condition. Understanding the pathomechanisms of itch will help to address the substantial burden of these chronic pruritic conditions.

Location
JW Marriot
1109 Brickell Ave 33131 Miami, FL United States
MAT-GLB-2306089 v1.0 02/2024

Speakers