Unique and Overlapping Roles of Type 2 Cytokines in AD and PN

• Recognize characteristics and disease burden of atopic dermatitis (AD) and prurigo nodularis (PN)
• Describe how AD and PN are distinct diseases and how some patients may experience both
• Examine how type 2 inflammation drives pruritus and cutaneous tissue manifestations, thus playing a key role in both AD and PN pathophysiology

In this ADVENT symposium at the 2023 AAD annual meeting, “Prurigo Nodularis and Atopic Dermatitis: Distinct Diseases With Shared and Unique Roles for Type 2 Inflammation”, Sarina Elmariah, MD, PhD, MPH (University of California San Francisco), Brian Kim, MD, MTR (Icahn School of Medicine at Mount Sinai), and Shawn Kwatra, MD (Johns Hopkins University School of Medicine), reviewed the clinical presentation and disease burden of prurigo nodularis (PN) and atopic dermatitis (AD), and the role that type 2 inflammation plays in the development of these two chronic pruritic diseases.