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Dermatology

Interactions of Type 2 Inflammation on Epidermal Abnormalities: Barrier Dysfunction and Microbial Dysbiosis

Insights from ESDR 2022 ADVENT symposium, examining how type 2 inflammation impacts skin barrier components and the microbiome in atopic dermatitis.

Lisa Beck
MD
Lisa Beck

Learning objectives

  • Describe the interactions between type 2 inflammation and the skin barrier that drive atopic dermatitis
  • Explore the role of the neuroimmune axis in pruritus
  • Review results of recent studies targeting type 2 inflammation to improve or normalize skin barrier function in atopic dermatitis

Description

Skin barrier dysfunction and neuroimmune dysfunction are hallmarks of atopic dermatitis, that are driven in part by type 2 inflammation. In this ADVENT-sponsored symposium at the ESDR Congress in Amsterdam, experts Laurent Misery, MD, PhD (University Hospital of Brest, France), Lisa Beck, MD (University of Rochester, USA), and Simon Danby, PhD (University of Sheffield, UK), examined the ways in which type 2 inflammation impacts and influences the skin barrier in atopic dermatitis.

MAT-GLB-2204798 V2 11/2022

About this expert

Dermatology

Lisa Beck

MD

Goldsmith Professor of Dermatology, University of Rochester Medical Center, New York, United States

See author’s profile
Lisa Beck

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