16 search results for: biomarkers

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Potential Biomarkers of Subclinical Control in AD Pathophysiology

Dr. Amy Paller describes potential biomarkers of subclinical control at EADV 2025

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Which Biomarkers of AD Might Be Robust Enough to Be Evaluated as a Measure of Disease Modification?

In this soundbite video from the April 2025 ADVENT Forum in Lisbon, Portugal, Prof. Oscar Palomares reviews the cellular and molecular pathways underlying atopic dermatitis and considers which biomarkers may one day serve as robust measures of disease modification, despite no validated options currently being available.

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Navigating Complex Definitions: Early Intervention and Disease Modification in Atopic Dermatitis

Dr. Amy Paller discusses the evolving concepts of early intervention and disease modification in AD and describes potential biomarkers of subclinical control at EADV 2025.

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The Burden of a Lifetime: Can Disease Modification Rewrite the Narrative of Atopic Dermatitis?

Professors Bouaziz, Paller, and Irvine discuss the clinical burden of atopic dermatitis, the biomarkers of subclinical control, and evidence of potential disease modification in AD at EADV 2025.

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On the Surface: Restoring the Skin Barrier in Patients With AD

In this video from the April 2025 WCPD symposium, Dr Amy Paller discusses the pathophysiology of skin barrier dysfunction in AD and how regulating IL-4 and IL-13 signaling may lead to restoration of the skin barrier. Dr Paller goes on to explore how reducing certain biomarkers, such as CCL17 (TARC), may reduce inflammation that contributes to AD severity in pediatric patients.

Simon Couillard
Expert
Simon Couillard, MD, MSc

Professor Couillard is a respirologist and the Québec Lung Association Chair of Respiratory Research at the Université de Sherbrooke, Canada. He leads a team investigating ways to use biomarkers to predict and prevent asthma attacks and improve asthma management.

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Both Clinical and Subclinical Disease Control Are Important to Achieve Disease Modification in AD

In this soundbite video from the April 2025 ADVENT Forum in Lisbon, Portugal, Dr. Eric Simpson explains how both clinical and subclinical disease control are critical for achieving true disease modification in atopic dermatitis, emphasizing the role of biomarkers in predicting long-term outcomes and guiding treatment decisions.

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Charting the Future: Preventing the Atopic March

In this video from the April 2025 WCPD symposium, Dr Eulàlia Baselga discusses how early intervention during infancy and childhood in patients with AD may reduce the progression of the atopic march. Dr Baselga goes on to review data showing how the reduction of biomarkers such as IgE and CCL17 may reduce inflammation and sensitization that contribute to atopic comorbidities.

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CCL17 (TARC): A Key Player and Biomarker in Atopic Dermatitis

An infographic to explore the the key roles of CCL17 (TARC) in atopic dermatitis.

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The Burden of a Lifetime: Can Disease Modification Rewrite the Narrative of Atopic Dermatitis?

Join Professors Jean-David Bouaziz, Amy Paller, and Alan Irvine for a dynamic presentation on the multifaceted burden of atopic dermatitis, the evolving concept of disease modification, and how targeted systemic therapies may help improve long-term patient outcomes.