67 search results for: mechanism of disease

Expert Interview: Featuring Dr Shawn Kwatra on PN itch and impact on patients
expert video

Expert Interview: Featuring Dr Shawn Kwatra on PN itch and impact on patients

Dermatology
Join Dr Kwatra as he dives deeper into the mechanism of lesion formation in Prurigo Nodularis and the impact the development of these skin lesions have on patient life.
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ADVENT On Air - Dermatology
Podcast

ADVENT On Air | Expert Discussions in Dermatology

Dermatology
Listen to the latest updates in type 2 inflammatory science and associated skin diseases, brought to you by leading dermatology experts in the field. ADVENT On Air podcasts feature scientific conversations that explore new research into the pathophysiology, clinical features, and disease burden for a range of dermatological diseases linked to type 2 inflammation, including atopic dermatitis (AD) and prurigo nodularis (PN). Hear new insights revealed through expert-led conversations below or in your preferred podcast app.

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CRSwNP Triathlon: An Interactive Learning Experience
interactivity

CRSwNP Triathlon: An Interactive Learning Experience

Rhinology
Embark on this interactive triathlon challenge to uncover the interplay of type 2 inflammation, barrier dysfunction, and neuroimmune dysregulation in the disease pathology of CRSwNP.
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Itch: The Common Thread in Dermatological Type 2 Inflammation (AD, PN, and CSU)​ - Panel Discussion
expert video

Itch: The Common Thread in Dermatological Type 2 Inflammation (AD, PN, and CSU)​ - Panel Discussion

Dermatology
Panel discussion exploring how itch differs across AD, PN, and CSU, and how it affects pediatric patients with AD.
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The Impact <b>of</b> Skin Fibrosis in Patients with Prurigo Nodularis
videoanimation

The Impact of Skin Fibrosis in Patients with Prurigo Nodularis

Dermatology
An animated infographic exploring the patient burden and pathophysiology of skin fibrosis in prurigo nodularis, specifically detailing how fibrotic pathways are driven and the key molecules involved.
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A brief overview <b>of</b> the pathophysiology <b>of</b> PN
expert video

A brief overview of the pathophysiology of PN

Dermatology
Dr. Chovatiya explains that PN is primarily a chronic itch disease with a complex pathophysiology involving neuronal changes, type 2 inflammation, and fibrotic skin processes, affecting patients' overall well-being.
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Contributions <b>of</b> Type 2 Cytokines to Chronic Pruritus in AD, PN, and CSU
expert video

Contributions of Type 2 Cytokines to Chronic Pruritus in AD, PN, and CSU

Dermatology
Dr. Elmariah introduces the multiple roles of type 2 cytokines in chronic itch.
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Can Chronic Rhinosinusitis With Nasal Polyps be Considered in Remission if the Patient has an Impaired Sense <b>of</b> Smell?
expert video

Can Chronic Rhinosinusitis With Nasal Polyps be Considered in Remission if the Patient has an Impaired Sense of Smell?

Rhinology
Dr. Backer discusses assessing remission in CRSwNP by evaluating the patient's sense of smell in this video clip from the EAACI 2024 symposium.
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The Evolving Understanding <b>of</b> Prurigo Nodularis (PN) Has Implications for Patient Management
Infographic

The Evolving Understanding of Prurigo Nodularis (PN) Has Implications for Patient Management

Dermatology
An infographic summarizing the clinical manifestations and pathophysiological processes of PN.
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How Does Protective Type 2 Immunity Become Harmful Type 2 Inflammation?
expert video

How Does Protective Type 2 Immunity Become Harmful Type 2 Inflammation?

Dermatology
In this video from the March 2025 ADVENT symposium in Orlando, Florida, Dr. Eric Simpson discusses how protective type 2 immunity can become dysregulated, leading to harmful type 2 inflammation. The associated inflammatory process can contribute to the pathophysiology of several dermatological diseases, including AD, PN, CSU, and BP.
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The Impact <b>of</b> Skin Dysbiosis on Atopic Dermatitis
expert video

The Impact of Skin Dysbiosis on Atopic Dermatitis

Dermatology
Dr. Lisa Beck highlights key data from the ADRN Study demonstrating the correlation between skin dysbiosis, S. aureus colonization, and atopic dermatitis severity.
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What contributes more to loss <b>of</b> smell in patients with CRSwNP: nasal obstruction or inflammation?
expert video

What contributes more to loss of smell in patients with CRSwNP: nasal obstruction or inflammation?

Rhinology
Prof. Mullol discusses the contribution of nasal obstruction and inflammation in loss of smell in patients with CRSwNP
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Sanofi and Regeneron are global leaders in pharmaceutical development, each with a long history of supporting frontline physicians to improve human health and reduce the burden of disease. Driven by the same commitment to patients and their families, Sanofi and Regeneron have partnered to take on type 2 inflammation and the range of chronic conditions in which excessive inflammation plays a role.

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