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87 search results for: mechanism of disease

Rhinology

Should we Still Operate on Patients With Chronic Rhinosinusitis With Nasal Polyps?

2 min

expert video

This video clip from the EAACI 2024 symposium discusses whether patients with CRSwNP should undergo a surgery.

Dermatology

On the Surface: Restoring the Skin Barrier in Patients With AD

17 min

expert video

In this video from the April 2025 WCPD symposium, Dr Amy Paller discusses the pathophysiology of skin barrier dysfunction in AD and how regulating IL-4 and IL-13 signaling may lead to restoration of the skin barrier. Dr Paller goes on to explore how reducing certain biomarkers, such as CCL17 (TARC), may reduce inflammation that contributes to AD severity in pediatric patients.

Dermatology

Skin Barrier Dysfunction and Type 2 Inflammation in Atopic Dermatitis

5 min

videoanimation

Learn more about how chronic and systemic type 2 inflammation contributes to skin barrier dysfunction in atopic dermatitis

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Sanofi and Regeneron are global leaders in pharmaceutical development, each with a long history of supporting frontline physicians to improve human health and reduce the burden of disease. Driven by the same commitment to patients and their families, Sanofi and Regeneron have partnered to take on type 2 inflammation and the range of chronic conditions in which excessive inflammation plays a role.

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