182 search results for: Pathophysiology
What Are the Key Inflammatory Processes in Patients with COPD?
Dr. Klaus Rabe, MD, PhD, discusses the key inflammatory processes in patients with COPD and their implications for patient care.
How Type 2 Inflammation Drives Eosinophils in Asthma
Explore how type 2 inflammation drives the production of eosinophils in severe asthma.
Exploring the Mechanisms of FeNO Production in the Lungs
Explore how type 2 inflammation drives the production of FeNO in severe asthma
Understanding the Contribution of IL-4 in the Development of Fibrosis in Prurigo Nodularis
Professor Sarina Elmariah highlights the multifaceted role of IL-4 and IL-13 in driving dermal fibrosis in prurigo nodularis, which leads to persistent scarring and dyspigmentation that significantly contribute to patients' embarrassment, anxiety, depression, and self-esteem.
Itch in Chronic Inflammatory Skin Diseases: Histaminergic and Nonhistaminergic Mechanisms and Role of IL-4 as a Central Orchestrator in Promoting Neuronal Sensitization
In this soundbite video from the April 2025 ADVENT Forum in Lisbon, Portugal, Dr. Brian Kim explores the histaminergic and nonhistaminergic mechanisms of itch, highlighting how type 2 cytokines like IL-4 serve as central orchestrators of neuronal sensitization and immune–nervous system cross-talk.
Beyond Itch: The Multifaceted Role of IL-4/IL-13 in the Pathogenesis of PN
Professor Sarina Elmariah describes how IL-4 and IL-13, key drivers of type 2 inflammation, uniquely contribute to manifestations of prurigo nodularis beyond itch.
Pathways Driving Chronic Airway Remodeling in Asthma
See how type 2 inflammation underlies remodeling processes in asthma.
Exploring the Potential Role of Biomarkers in Managing Bullous Pemphigoid
Dr. Donna Culton discusses biomarkers in bullous pemphigoid and considers their potential clinical use.
The Heterogeneity of Underlying Inflammation in Patients With COPD
Join global expert Professor Ian Pavord as he discusses the heterogeneity of underlying inflammation in patients with COPD.
What Do We Know About Type 2 Inflammation in COPD?
Join global expert Dr. Michael Wechsler as he discusses type 2 inflammation in COPD.
CCL17 (TARC): A Key Player and Biomarker in Atopic Dermatitis
An infographic to explore the the key roles of CCL17 (TARC) in atopic dermatitis.
Clinical Manifestations Associated With Airway Remodeling in Asthma
Join Dr. Hanania to understand how to identify patients at risk of fixed airway obstruction in clinical settings.
