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Pulmonology

Understanding IL-33: A Key Factor in COPD Pathogenesis

Explore the role of interleukin (IL)-33 in chronic obstructive pulmonary disease (COPD) pathophysiology and its potential as a therapeutic target.

Learning objectives

  • Describe the mechanism of action of IL-33 in driving inflammation in COPD
  • Identify the cells and pathways involved in IL-33 signaling and its downstream effects
  • Explain the correlation between IL-33 levels and COPD severity and exacerbation risk

Description

Examine the role of IL-33, a tissue-derived cytokine, in the pathophysiology of COPD, focusing on its activation of pro-inflammatory pathways and its association with disease severity and exacerbation risk. Explore the mechanisms by which IL-33 drives inflammation, including the key cells and signaling pathways involved in COPD.

MAT-GLB-2407955 - 2.0 - 05/2025

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