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59 search results for: itch

The Pathophysiology of Prurigo Nodularis
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The Pathophysiology of Prurigo Nodularis

Dermatology
An infographic exploring the pathophysiology of prurigo nodularis and the role of type 2 inflammation.
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Under the <b>Itch</b>y Surface: The Insidious, Cumulative Burden of Type 2 Inflammation in AD
expert video

Under the Itchy Surface: The Insidious, Cumulative Burden of Type 2 Inflammation in AD

Dermatology
In this video from the March 2025 ADVENT symposium in Orlando, Florida, Dr. Eric Simpson discusses the systemic nature of atopic dermatitis (AD) and how the disease burden extends beyond the skin. Through the lens of cumulative life course impairment, Dr. Simpson goes on to explore how persistent type 2 inflammation in AD may drive both atopic and nonatopic comorbidities, emphasizing the potential importance of early and effective therapeutic intervention to alter disease progression
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Type 2 Inflammation and Neuronal Sensitization in AD and PN
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Type 2 Inflammation and Neuronal Sensitization in AD and PN

Dermatology
Mechanisms of itch in normal skin and the effect of type 2 inflammation on neurons leading to chronic itch in atopic dermatitis and prurigo nodularis.
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Contributions of Type 2 Cytokines to Chronic Pruritus in AD, PN, and CSU
expert video

Contributions of Type 2 Cytokines to Chronic Pruritus in AD, PN, and CSU

Dermatology
Dr. Elmariah introduces the multiple roles of type 2 cytokines in chronic itch.
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Type 2 Inflammation and Neuroimmune Axis Dysregulation in AD, PN, and CSU
expert video

Type 2 Inflammation and Neuroimmune Axis Dysregulation in AD, PN, and CSU

Dermatology
Examination of the unique ways type 2 inflammation contributes to itch in AD, PN, and CSU.
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AD, PN, and CSU: Distinct, Pruritic Diseases
expert video

AD, PN, and CSU: Distinct, Pruritic Diseases

Dermatology
Dr. Elmariah explains how AD, PN, and CSU are distinct diseases with the common, burdensome symptom of itch.
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Neuroimmune Axis Dysregulation and Type 2 Inflammation: Shared Roles in AD, PN, and CSU
expert video

Neuroimmune Axis Dysregulation and Type 2 Inflammation: Shared Roles in AD, PN, and CSU

Dermatology
Exploration of the shared type 2 inflammation and neuroimmune axis dysfunction in AD, PN, and CSU leading to itch.
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Immune System, Microbiome and Neuroimmune Crosstalk in the Skin: Implications for AD
expert video

Immune System, Microbiome and Neuroimmune Crosstalk in the Skin: Implications for AD

Dermatology
The role of dysbiosis in the propagation of type 2 inflammation and itch in atopic dermatitis – a presentation from the ADVENT symposium at ISID 2023.
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The Burden of Atopic Dermatitis in Children – Daily Pruritis and Sleep Disturbance 
expert video

The Burden of Atopic Dermatitis in Children – Daily Pruritis and Sleep Disturbance 

Dermatology
Dr. Mark Koh provides insights on itch and its impact on sleep in children with AD.
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Inside the Hive: Type 2 Inflammatory Pathways in Chronic Spontaneous Urticaria
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Inside the Hive: Type 2 Inflammatory Pathways in Chronic Spontaneous Urticaria

Dermatology
Join Dr. Jason Hawkes in discussing the burden of CSU and how type 2 inflammation contributes to the development of chronic wheals (hives) and angioedema
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Emerging Therapeutic Landscape and Implications for Patient Management in PN​
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Emerging Therapeutic Landscape and Implications for Patient Management in PN​

Dermatology
A review of disease burden and treatment needs in PN, and how current and emerging therapies can impact patient management.
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ADVENT On Air | Exploring PN as a Distinct and Unique Disease
Podcast

ADVENT On Air | Exploring PN as a Distinct and Unique Disease

Dermatology
Dr. Sonja Ständer and Dr. Shawn Kwatra discuss the unique features of prurigo nodularis (PN) as well as the characteristics that are shared with atopic dermatitis, and aim to raise awareness of PN among both physicians and patients.
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Sanofi and Regeneron are global leaders in pharmaceutical development, each with a long history of supporting frontline physicians to improve human health and reduce the burden of disease. Driven by the same commitment to patients and their families, Sanofi and Regeneron have partnered to take on type 2 inflammation and the range of chronic conditions in which excessive inflammation plays a role.

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