72 search results for: asthma

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Airway Hyperresponsiveness In Asthma Is Mainly Driven By Components Of Type 2 Inflammation

Examine underlying type 2 inflammation as a driver of airway hyperresponsiveness in patients with asthma.

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Airway Hyperresponsiveness In Asthma Is Mainly Driven By Components Of Type 2 Inflammation

Examine underlying type 2 inflammation as a driver of airway hyperresponsiveness in patients with asthma.

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Pediatric Asthma Trajectory and Clinical Remission

Join Dr. Leonard Bacharier as he discusses the definition of clinical remission in pediatric asthma and how it can represent a potential target in pediatric asthma management.

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The Burden in Patients with CRSwNP and Coexisting Asthma

This video supports improved clinical awareness and encourages comprehensive care strategies for patients living with both CRSwNP and asthma.

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Mucus Plugging as a Potential Target in Asthma Management

Join Dr. Celeste Porsbjerg as she explores the mechanisms underlying mucus plugging development as mucociliary clearance. She explains how type 2 cytokines—particularly IL-13—impair this clearance mechanism, leading to mucus plugging, and worsened asthma outcomes.

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A view into the Airway: The Pathophysiology and Clinical Relevance of Mucus Plugs in Asthma

Explore the role of type 2 inflammation in the production of mucus plugs in asthma and the effects these plugs can have on patients.

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Role of Type 2 Cytokines in Asthma and COPD

Dr Mario Castro explains how type 2 cytokines play a crucial role in airway remodeling and inflammation in asthma and COPD, impacting patient outcomes.

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ERS 2024 | Panel Discussion: What Might Be Required for On-Therapy Remission in Pediatric Severe Asthma?

In this ADVENT symposium at the 2024 European Respiratory Society conference, Drs. Sharon Dell and Leonard Bacharier discuss the potential domains of on therapy clinical remission in pediatric severe asthma, emphasizing lung function as a key parameter for children.

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Mucus Plugging Is a Key Component of Remodeling in Asthma, Leading to Fixed Airway Obstruction

Learn about the role of type 2 inflammation in the burden and pathophysiology of mucus plugging in severe asthma

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ERS 2025 | Type 2 Severe Asthma "Unplugged": Reducing Mucus to Improve Long-term Patient Outcomes

Join leading pulmonologists Drs. Njira Lugogo, Simon Couillard, and Mario Castro, as they explore the role of type 2 inflammation in the pathogenesis of mucus plugging in the airways, the burden of excess mucus in patients with moderate-to-severe asthma, and how reducing airway mucus may lead to improved long-term patient outcomes.

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Unraveling the Link of Type 2 Inflammation and Airway Remodeling in Asthma

Join Dr. Celeste Porsbjerg as she discussed on how type 2 inflammation may lead to airway remodeling in asthma, exploring the pathophysiologic mechanisms, that ultimately lead to structural changes and irreversible loss of lung function

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CRSwNP at Center Stage: Impact of Biologics in Patients with Co-existing Type 2 Asthma

In this video soundbite from the EAACI 2025 symposium, Dr. Philippe Gevaert explains how biologic options for uncontrolled CRSwNP are increasing, and phase 3 studies of approved biologics show improved outcomes and decreased SCS use/surgery in patients with CRSwNP. Additionally, he explains how biologics targeting type 2 inflammatory pathophysiology potentially improve outcomes for eligible patients with co-existing CRSwNP and asthma.