40 search results for: mechanism of disease

Type 2 Inflammation Alters the Structure and Function <b>of</b> the Skin in AD
expert video

Type 2 Inflammation Alters the Structure and Function of the Skin in AD

Dermatology
Highlights from the WCD 2023 ADVENT symposium, analyzing case studies and linked comorbidities in relation to atopic dermatitis and prurigo nodularis.
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How Does Protective Type 2 Immunity Become Harmful Type 2 Inflammation?
expert video

How Does Protective Type 2 Immunity Become Harmful Type 2 Inflammation?

Dermatology
In this video from the March 2025 ADVENT symposium in Orlando, Florida, Dr. Eric Simpson discusses how protective type 2 immunity can become dysregulated, leading to harmful type 2 inflammation. The associated inflammatory process can contribute to the pathophysiology of several dermatological diseases, including AD, PN, CSU, and BP.
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Skin Barrier, Neuroimmune Axis, and Type 2 Inflammation in Atopic Dermatitis
expert video

Skin Barrier, Neuroimmune Axis, and Type 2 Inflammation in Atopic Dermatitis

Dermatology
Presentations from the ADVENT symposium at the ISID 2023 meeting on the skin barrier, neuroimmune axis, and type 2 inflammation in atopic dermatitis.
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Key Type 2 Cytokines Impact the Skin Microbiome in Atopic Dermatitis
expert video

Key Type 2 Cytokines Impact the Skin Microbiome in Atopic Dermatitis

Dermatology
Dr. Stephan Weidinger explains how type 2 cytokines impact the skin microbiome in AD.
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The Impact <b>of</b> Skin Dysbiosis on Atopic Dermatitis
expert video

The Impact of Skin Dysbiosis on Atopic Dermatitis

Dermatology
Dr. Lisa Beck highlights key data from the ADRN Study demonstrating the correlation between skin dysbiosis, S. aureus colonization, and atopic dermatitis severity.
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Evaluating the Responses to Biologic Therapies in Children With Atopic Dermatitis
expert video

Evaluating the Responses to Biologic Therapies in Children With Atopic Dermatitis

Dermatology
Dr. Amy Paller shares her opinion on practical considerations for evaluating response during treatment with biologics in children with atopic dermatitis.
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The Implications <b>of</b> Sweat Duct Dysfunction and the Microbial Dysbiosis in AD
expert video

The Implications of Sweat Duct Dysfunction and the Microbial Dysbiosis in AD

Dermatology
Dr. Lisa Beck talks about sweat duct dysfunction and the impact of S. aureus colonization.
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The Role <b>of</b> Epithelial Barrier Components in AD: Insights and Implications
expert video

The Role of Epithelial Barrier Components in AD: Insights and Implications

Dermatology
Dr. Lisa Beck explains the role of epithelial barrier components and barrier disruption in AD.
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The Role <b>of</b> Type 2 Inflammation in Skin Barrier Dysfunction in Atopic Dermatitis
expert video

The Role of Type 2 Inflammation in Skin Barrier Dysfunction in Atopic Dermatitis

Dermatology
Dr. Robert Bissonnette highlights the role of type 2 inflammation in skin barrier dysfunction in atopic dermatitis.
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AD and PN: Commonalities and Differences – A Case Study
expert video

AD and PN: Commonalities and Differences – A Case Study

Dermatology
Highlights from the WCD 2023 ADVENT symposium, analyzing case studies and linked comorbidities in relation to atopic dermatitis and prurigo nodularis.
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What Went Wrong? How Dysregulated Type 2 Immunity Contributes to AD, PN, CSU, and BP
expert video

What Went Wrong? How Dysregulated Type 2 Immunity Contributes to AD, PN, CSU, and BP

Dermatology
This full video presentation of the March 2025 ADVENT cross-dermatology symposium, hosted in Orlando, Florida features Dr. Eric Simpson, Dr. Shawn Kwatra, Dr. Jason Hawkes and Dr. Victoria Werth. The faculty present the latest information around type 2 inflammation and its association with atopic dermatitis (AD), prurigo nodularis (PN), chronic spontaneous urticaria (CSU) and bullous pemphigoid (BP).
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Barrier Tight Junction Disruption in Atopic Dermatitis
expert video

Barrier Tight Junction Disruption in Atopic Dermatitis

Dermatology
Explore tight junction function in the skin and the impact of its disruption in atopic dermatitis – a soundbite from the ESDR Symposium 2022.
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Sanofi and Regeneron are global leaders in pharmaceutical development, each with a long history of supporting frontline physicians to improve human health and reduce the burden of disease. Driven by the same commitment to patients and their families, Sanofi and Regeneron have partnered to take on type 2 inflammation and the range of chronic conditions in which excessive inflammation plays a role.

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