World Congress of Dermatology (WCD) 2023 | Singapore

• Examine the challenges faced by dermatologists when managing moderate-to-severe atopic dermatitis in children (<12 years)
• Explore the relevance of targeting type 2 inflammation and the implications for disease course modification in childhood
• Review emerging data on treatment options and practical management of children with moderate-to-severe AD
• Recognize that atopic dermatitis and prurigo nodularis are distinct diseases with commonalities and differences in clinical and pathophysiological characteristics
• Review barrier dysfunction in atopic dermatitis, and share evidence supporting skin barrier normalization achieved by inhibiting type 2 cytokines
• Review the role of type 2 cytokines in dermal fibrosis, and pruritus in prurigo nodularis

Atopic Dermatitis (AD) in Children: Early Intervention Can Reduce Long-Term Disease Impact 

In the ADVENT symposium at the 2023 World Congress of Dermatology, entitled “Atopic Dermatitis in Children: Early Intervention Can Reduce Long-Term Disease Impact”, experts Amy Paller, MD (Northwestern University, USA), Mark Koh, MD (KK Women’s & Children’s Hospital, Singapore), Stephan Weidinger, MD, PhD (Christian-Albrecht University, Kiel, Germany), and Elaine Siegfried, MD (Saint Louis University School of Medicine, USA), delved into the challenges and advancements in the management of moderate-to-severe atopic dermatitis in pediatric patients. The presentations emphasized the significance of targeting type 2 inflammation, explored implications for disease course modification during childhood, and provided insights into emerging treatment options and practical management strategies for children with moderate-to-severe atopic dermatitis.

IL-4 and IL-13: Shared and Unique Roles in Atopic Dermatitis (AD) and Prurigo Nodularis (PN)

Atopic dermatitis and prurigo nodularis are dermatological conditions characterized by both common and distinct factors influencing their pathophysiology, presentation, and progression. In this ADVENT-sponsored symposium at the WCD 2023 Congress in Singapore, experts Mark Tang, MD (Mount Alvernia Hospital, Singapore), Lisa A. Beck, MD (University of Rochester, USA), and Gil Yosipovitch, MD (Miami Itch Center, USA), examined the shared and distinct clinical features between atopic dermatitis and prurigo nodularis.