47 search results for: chronic inflammation

A brief overview of the pathophysiology of PN
expert video

A brief overview of the pathophysiology of PN

Dermatology
Dr. Chovatiya explains that PN is primarily a chronic itch disease with a complex pathophysiology involving neuronal changes, type 2 inflammation, and fibrotic skin processes, affecting patients' overall well-being.
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What role does IL-4 and IL-13 have in driving Type 2 inflammatory skin disease (AD, PN, CSU)?
expert video

What role does IL-4 and IL-13 have in driving Type 2 inflammatory skin disease (AD, PN, CSU)?

Dermatology
Dr. Oscar Palomares explains that IL-4 and IL-13 are crucial cytokines in type 2 inflammation, playing both unique and overlapping roles, including T cell expansion and contributing to clinical symptoms in chronic diseases.
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Impact of Exacerbations in COPD
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Impact of Exacerbations in COPD

Type 2 Inflammation
Dr. Stephanie Christenson discusses the association between COPD exacerbations and the increased risks of morbidity and mortality
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Exacerbations Lead to Worsening Lung Function
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Exacerbations Lead to Worsening Lung Function

Type 2 Inflammation
Dr. Mario Castro discusses how COPD exacerbations can predict future exacerbations and lead to progressive lung function loss in COPD patients.
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The Pathophysiology of Prurigo Nodularis
videoanimation

The Pathophysiology of Prurigo Nodularis

Dermatology
An infographic exploring the pathophysiology of prurigo nodularis and the role of type 2 inflammation.
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The Burden of <b>Chronic</b> Spontaneous Urticaria: One Patient’s Journey to Diagnosis
videoanimation

The Burden of Chronic Spontaneous Urticaria: One Patient’s Journey to Diagnosis

Dermatology
Learn about the clinical presentation of CSU and the burden many CSU patients face by following one patient’s journey from symptom presentation to CSU diagnosis in this 5-minute video.
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Multidisciplinary Partnership for Type 2 Inflammatory Diseases
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Multidisciplinary Partnership for Type 2 Inflammatory Diseases

Type 2 Inflammation
Drs. Thomas Casale, Mario Castro and Profs. Peter Hellings, Ian Pavord, Ulrike von Arnim, and Stephan Weidinger discuss multidisciplinary care
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What Went Wrong? How Dysregulated Type 2 Immunity Contributes to AD, PN, CSU, and BP
expert video

What Went Wrong? How Dysregulated Type 2 Immunity Contributes to AD, PN, CSU, and BP

Dermatology
This full video presentation of the March 2025 ADVENT cross-dermatology symposium, hosted in Orlando, Florida features Dr. Eric Simpson, Dr. Shawn Kwatra, Dr. Jason Hawkes and Dr. Victoria Werth. The faculty present the latest information around type 2 inflammation and its association with atopic dermatitis (AD), prurigo nodularis (PN), chronic spontaneous urticaria (CSU) and bullous pemphigoid (BP).
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UCARE 2023: Role of Type 2 <b>Inflammation</b> in CSU Pathogenesis 
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UCARE 2023: Role of Type 2 Inflammation in CSU Pathogenesis 

Dermatology
Dr. Saini provides a deep dive into the pathophysiology of type 2 inflammation in CSU.
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Overview of Type 2 <b>Inflammation</b> in the Presentations of AD, PN, and CSU
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Overview of Type 2 Inflammation in the Presentations of AD, PN, and CSU

Dermatology
Dr. Eric Simpson summarizes the role of type 2 inflammation in the clinical manifestations of AD, PN, and CSU.
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UCARE 2023: Neuronal Involvement in CSU
expert video

UCARE 2023: Neuronal Involvement in CSU

Dermatology
Dr. Kim provides a deep dive into the neuroimmune axis in CSU.
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Itch: The Common Thread in Dermatological Type 2 <b>Inflammation</b> (AD, PN, and CSU)​
expert video

Itch: The Common Thread in Dermatological Type 2 Inflammation (AD, PN, and CSU)​

Dermatology
A review of the shared and unique neuroimmune mechanisms in the generation of itch across AD, PN, and CSU.
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Sanofi and Regeneron are global leaders in pharmaceutical development, each with a long history of supporting frontline physicians to improve human health and reduce the burden of disease. Driven by the same commitment to patients and their families, Sanofi and Regeneron have partnered to take on type 2 inflammation and the range of chronic conditions in which excessive inflammation plays a role.

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