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Dermatology

Neuroimmune Axis in Atopic Dermatitis

A review of the neuroimmune mechanisms and changes to skin barrier that result in itch in AD.
Eric Simpson
MD
Eric Simpson

Learning objectives

  • Discuss the pathophysiological processes mediating pruritus in AD and PN
  • Describe how type 2 inflammatory cytokines are involved in inducing and amplifying pruritus in AD and PN
  • Explore the shared and distinct mechanisms of pruritus in AD and PN

Description

In the ADVENT Event at the 2023 ADVENT FORUM, Drs. Stephan Weidinger, Eric Simpson and Raj Chovatiya discussed the shared and unique neuroimmune mechanisms and supporting data demonstrating the generation of itch across AD and PN.

Tags
itchmechanism of diseaseneuroimmune mechanismstype 2 inflammation
MAT-GLB-2306039 V1 12/2023

About this expert

Dermatology

Eric Simpson

MD

Professor of Dermatology, School of Medicine, Oregon Health & Science University, Portland, US

See author’s profile
Eric Simpson

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Sanofi and Regeneron are global leaders in pharmaceutical development, each with a long history of supporting frontline physicians to improve human health and reduce the burden of disease. Driven by the same commitment to patients and their families, Sanofi and Regeneron have partnered to take on type 2 inflammation and the range of chronic conditions in which excessive inflammation plays a role.

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