In this ADVENT symposium at the 2024 EADV meeting, Professor Dedee Murrell is joined by colleagues Dr. Donna Culton, Professor Joost Meijer and Professor Enno Schmidt to provide updates for HCPs who treat patients with bullous pemphigoid (BP), a chronic relapsing autoimmune inflammatory skin disease. There is a need to better understand the complex mechanisms, involving autoimmunity and type 2 inflammation, which give rise to lesions, itch, and pain, the burdensome hallmark symptoms of BP. Current management guidelines, treatment challenges, and potential opportunities with targeted therapies will also be discussed.