115 search results for: Pathophysiology

Role of Type 2 Inflammation in Skin Barrier Disruption and Itch
Dermatology
Role of Type 2 Inflammation in Skin Barrier Disruption and Itch
expert video

In this highlight video from the October 2024 ADVENT symposium at EAPS in Vienna, Austria, Dr Christine Bangert discusses how type 2 inflammation contributes to epidermal barrier dysfunction and chronic itch in AD

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IL-4 Contributes to Systemic Type 2 Inflammation in AD
Dermatology
IL-4 Contributes to Systemic Type 2 Inflammation in AD
expert video

In this highlight video from the ADVENT AD symposium held at EADV’s 2024 Annual Meeting in Amsterdam, Dr. Stephan Weidinger discusses how IL-4 contributes to systemic type 2 inflammation in AD via several mechanisms, including T cell differentiation, B cell activation and IgE generation, and T regulatory cell inhibition.

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Type 2 Inflammation Within Skin Tissue in AD
Dermatology
Type 2 Inflammation Within Skin Tissue in AD
expert video

In this highlight video from the September 2024 ADVENT symposium at EADV’s Annual Meeting in Amsterdam, the Netherlands, Dr. Stephan Weidinger discusses how type 2 inflammation contributes to epidermal barrier dysfunction, perivascular infiltration and plasma protein leakage, and chronic itch in AD.

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Airway Hyperresponsiveness In Asthma Is Mainly Driven By Components Of Type 2 Inflammation
Pulmonology
Airway Hyperresponsiveness In Asthma Is Mainly Driven By Components Of Type 2 Inflammation
interactivity

Examine underlying type 2 inflammation as a driver of airway hyperresponsiveness in patients with asthma.

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Connecting Type 2 Inflammation to CRSwNP
Rhinology
Connecting Type 2 Inflammation to CRSwNP
expert video

Prof. Claus Bachert describes how type 2 inflammation drives CRSwNP.

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Can Therapy-Free Disease Control Be Achieved in Atopic Dermatitis?
Dermatology
Can Therapy-Free Disease Control Be Achieved in Atopic Dermatitis?
expert video

In this soundbite video from the April 2025 ADVENT Forum in Lisbon, Portugal, Prof. Thomas Bieber discusses emerging evidence that therapy-free disease control may be possible in atopic dermatitis, citing pediatric dupilumab data showing that a subset of patients-maintained remission after treatment discontinuation.

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Low Disease Activity and Disease Stability: Setting New Goals for COPD Care
Pulmonology
Low Disease Activity and Disease Stability: Setting New Goals for COPD Care
Infographic

This infographic explores the emerging concepts of disease activity, disease stability, and disease control in COPD.

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Both Clinical and Subclinical Disease Control Are Important to Achieve Disease Modification in AD
Dermatology
Both Clinical and Subclinical Disease Control Are Important to Achieve Disease Modification in AD
expert video

In this soundbite video from the April 2025 ADVENT Forum in Lisbon, Portugal, Dr. Eric Simpson explains how both clinical and subclinical disease control are critical for achieving true disease modification in atopic dermatitis, emphasizing the role of biomarkers in predicting long-term outcomes and guiding treatment decisions.

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ADVENT On Air | Back Again: Predicting Recurrence in Chronic Rhinosinusitis with Nasal Polyps
Rhinology
ADVENT On Air | Back Again: Predicting Recurrence in Chronic Rhinosinusitis with Nasal Polyps
Podcast

Learn from Drs. Buchheit and Wagenmann as they discuss key patient traits that predict disease recurrence in CRSwNP.

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Understanding Barriers to Advanced Systemic Therapy in AD
Dermatology
Understanding Barriers to Advanced Systemic Therapy in AD
expert video

Dr. Jean-David Bouaziz highlights a study describing barriers to initiating advanced systemic therapy for AD at EADV 2025

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KOL Video Interview – Dr Paula Luna
Dermatology
KOL Video Interview – Dr Paula Luna
expert video

In this exclusive video interview, Dr Paula Luna discusses how disease modification can be defined in AD and how IgE may be used as a biomarker in AD.

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