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Type 2 Inflammation

Impact of Advanced Systemic Therapies on Disease Control in AD

Dr. Simpson discusses impact of advanced systemic therapies in AD, and the link between inhibition of type 2 inflammation and reduced IgE levels.

Eric Simpson
MD
Eric Simpson

Learning objectives

  • Understand the potential of disease modification in AD, with reference to the responses achieved with various approved therapies
  • Assess the impact of inhibition of type 2 inflammation and associated comorbidities, and explore as a potential avenue for disease modification

Description

Exploring the concept of disease control in AD. The discussion emphasizes the achievement of significant responses, such as EASI-90, with various approved agents, suggesting progress towards a remitted state. The discussion hovered around the potential of disease modification for sustained control over time. Lastly, the discussion explores the link between type 2 blockade and the reduction in IgE levels, suggesting a potential avenue for disease modification by influencing both the disease and associated comorbidities.

MAT-GLB-2402321- 2.0 - 01/2025

About this expert

Dermatology

Eric Simpson

MD

Professor of Dermatology, School of Medicine, Oregon Health & Science University, Portland, US

See author’s profile
Eric Simpson

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