Dr. Simpson discusses impact of advanced systemic therapies in AD, and the link between inhibition of type 2 inflammation and reduced IgE levels.
Exploring the concept of disease control in AD. The discussion emphasizes the achievement of significant responses, such as EASI-90, with various approved agents, suggesting progress towards a remitted state. The discussion hovered around the potential of disease modification for sustained control over time. Lastly, the discussion explores the link between type 2 blockade and the reduction in IgE levels, suggesting a potential avenue for disease modification by influencing both the disease and associated comorbidities.
Professor of Dermatology, School of Medicine, Oregon Health & Science University, Portland, US
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