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Type 2 Inflammation

In Chronic Pruritic Skin Diseases, the Neuroimmune Axis Involves Dynamic Interactions Between Type 2 Inflammation and Sensory Nerves

In this soundbite video from the April 2025 ADVENT Forum in Lisbon, Portugal, Dr. Brian Kim describes the dynamic neuroimmune interactions in chronic pruritic skin diseases, emphasizing how type 2 cytokines and sensory nerves actively influence both itch perception and tissue inflammation.
Brian Kim
MD
Brian Kim

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Learning objectives

  • Explain how select type 2 cytokines act directly on the nervous system to promote inflammation and itch
  • Discuss the concept of sensory nerves as active contributors to inflammation through neuropeptide release
  • Recognize how the neuroimmune axis shapes both pathophysiology and therapeutic response in chronic pruritic skin diseases
Tags
expert insightsmechanism of disease
MAT-GLB-2507496 - 1.0 - 01/2026

About this expert

Dermatology

Brian Kim

MD

Professor, Vice Chair of Research, and Site Chair of Mount Sinai West, Icahn School of Medicine, NY, US

See author’s profile
Brian Kim

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Sanofi and Regeneron are global leaders in pharmaceutical development, each with a long history of supporting frontline physicians to improve human health and reduce the burden of disease. Driven by the same commitment to patients and their families, Sanofi and Regeneron have partnered to take on type 2 inflammation and the range of chronic conditions in which excessive inflammation plays a role.

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