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Dermatology

The Role of Type 2 Inflammation in Skin Barrier Dysfunction in Atopic Dermatitis

Dr. Robert Bissonnette highlights the role of type 2 inflammation in skin barrier dysfunction in atopic dermatitis.

Robert Bissonnette
MD
Robert Bissonnette

Learning objectives

  • Explore the role of type 2 inflammation in skin barrier dysfunction in atopic dermatitis

Description

Dr. Robert Bissonnette explains how type 2 inflammation mediates skin barrier dysfunction in atopic dermatitis, including increased skin permeability and TEWL, modified structural and differentiation proteins, diminished tight junction function, impaired sweating faction, as well as dysbiosis and S. aureus colonization.
 

Tags
expert insightsmechanism of diseasesymposium
MAT-GLB-2305527 V1.0 01/2024

About this expert

Dermatology

Robert Bissonnette

MD

President of Innovaderm Research, Montréal, Quebec, Canada

See author’s profile
Robert Bissonnette

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Sanofi and Regeneron are global leaders in pharmaceutical development, each with a long history of supporting frontline physicians to improve human health and reduce the burden of disease. Driven by the same commitment to patients and their families, Sanofi and Regeneron have partnered to take on type 2 inflammation and the range of chronic conditions in which excessive inflammation plays a role.

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