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Type 2 Inflammation

From Protective Type 2 Immunity to Aberrant Type 2 Inflammation

In this soundbite video from the April 2025 ADVENT Forum in Lisbon, Portugal, Prof. Oscar Palomares explains how type 2 immunity evolved to protect against parasites, venoms, and toxins, and how its dysregulation can result in aberrant type 2 inflammation underlying multiple chronic inflammatory diseases.
Oscar Palomares
PhD
Oscar Palomares

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Learning objectives

  • Describe how type 2 cytokines disrupt epithelial barriers and promote allergen sensitization that may lead to atopic comorbidities
  • Examine mechanisms linking type 2 inflammation to impaired innate immune responses and heightened vulnerability to viral infections
  • Recognize how early-life barrier dysfunction in atopic dermatitis may influence the trajectory of comorbid atopic diseases
Tags
expert insightsmechanism of disease
MAT-GLB-2507496 - 1.0 - 01/2026

About this expert

Allergy/Immunology

Oscar Palomares

PhD

Complutense University of Madrid

See author’s profile
Oscar Palomares

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Sanofi and Regeneron are global leaders in pharmaceutical development, each with a long history of supporting frontline physicians to improve human health and reduce the burden of disease. Driven by the same commitment to patients and their families, Sanofi and Regeneron have partnered to take on type 2 inflammation and the range of chronic conditions in which excessive inflammation plays a role.

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