Itch: Neuroimmune Axis in Chronic Pruritic Skin Diseases
A review of the neuroimmune axis and the mechanisms involved in perpetuating chronic itch in AD, PN, and CSU.
Learning objectives
- Discuss the pathophysiological processes mediating pruritus in AD, PN, and CSU
- Describe how type 2 inflammatory cytokines are involved in inducing and amplifying pruritus in AD, PN, and CSU
- Explore the shared and distinct mechanisms of pruritus in AD, PN, and CSU
Description
In this ADVENT symposium at the 2023 ADVENT FORUM, “Itch: The Common Thread in Dermatological Type 2 Inflammation (AD, PN, & CSU)”, Stephan Weidinger, MD, PhD (University Hospital Schleswig-Holstein Campus Kiel, Kiel, Germany), Eric Simpson, MD, MCR (Oregon Health & Science University, Portland, OR, USA), Raj Chovatiya, MD, PhD (George Washington University School of Medicine and Health Sciences, Washington DC, USA) and Thomas B. Casale, MD (University of South Florida, USA) discussed the shared and unique neuroimmune mechanisms and supporting data demonstrating the generation of itch across AD, PN, and CSU.
About this expert
Stephan Weidinger
Professor and Chair for Dermatology at the Christian-Albrechts-University; Director of the Department of Dermatology and Allergy at the University Hospital Schleswig-Holstein, Campus Kiel, Germany
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